Illustration of people burying the dead from plague, history's deadliest disease
    camera-icon
  • Photo Credit: Wikimedia Commons

The Antonine Plague, 165-180

5 Million

The Justinian Plague, 541-542

25-50 Million

The Black Death, 1347-1351

75-200 Million

Illustration of the plague in Florence, deadliest diseases in history
    camera-icon
  • Illustration of the Plague in 1348 Florence.

    Photo Credit: Wikimedia Commons

Smallpox, 1520

8 Million

Illustration of Aztecs suffering from smallpox, one of history's deadliest diseases
    camera-icon
  • Illustration of Aztecs suffering from smallpox as shown in the 16th century Florentine Codex.

    Photo Credit: Wikimedia Commons

The Cocoliztli Epidemic, 1545

12-15 Million

The Third Cholera Pandemic, 1846-1860

Over 1 Million

Trench Fever, 1914-1918

3 Million

Soldiers being deloused on the Belgian Front to prevent trench fever, one of history's deadliest diseases
    camera-icon
  • Soldiers on the Belgian Front are deloused to prevent trench fever.

    Photo Credit: Wikimedia Commons

The Spanish Flu, 1918-1919

17-100 Million

The Asian Flu, 1957-1958

1-2 Million

The Hong Kong Flu, 1968

1-4 Million

The HIV/AIDS Crisis, 1981-1995

Over 30 Million

ACT UP activists protest at NIH in 1990, deadliest diseases in history
    camera-icon
  • ACT UP activists at the "Storm the NIH" protest movement in 1990.

    Photo Credit: NIH History Office / Flickr (Public domain)